LEGAL REGULATION ISSUES OF COPYRIGHT CIRCULATION IN UKRAINE

LEGAL REGULATION ISSUES OF copyright CIRCULATION IN UKRAINE

The aim of the article is a comparative legal study of laws and regulations that determine the legal principles for the regulation of copyright circulation in some foreign countries and in Ukraine and, on this basis, a definition of ways to improve domestic legislation in this sphere.The subject of the study is an interrogation of legal regulation

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Substrate-induced unfolding of protein disulfide isomerase displaces the cholera toxin A1 subunit from its holotoxin.

To generate a cytopathic effect, the catalytic A1 subunit of cholera toxin (CT) must be separated from the rest of the toxin.Protein disulfide isomerase (PDI) is thought to mediate CT disassembly by acting as a redox-driven chaperone that actively unfolds the CTA1 subunit.Here, we show that PDI itself unfolds upon contact with CTA1.The substrate-in

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